Found 14 matching trials
Durability of Protection After Single Immunisation With GA2 Sporozoites (CoGA-Rechallenge)
PHASE1This study will assess the durability of protection of a single immunisatio...
Location
Multiple Locations
Evaluate the Infectivity Equivalence of Current and New Lots of Plasmodium Falciparum Strain NF54
PHASE1Objectives:
Primary:
• To characterize the infectivity of the new lot of ...
Location
Walter Reed Army Institute of Research
Trial to Evaluate the Safety, Immunogenicity and Protective Efficacy of Three or Five Administrations of GAP3KO Sporozoites
PHASE1This Phase 1 trial will include 16 subjects who will receive the Geneticall...
Location
Kaiser Permanente Washington Health Research Institute
Target Antigens Induced by Plasmodium Falciparum Sporozoite Immunization Under Chemoprophylaxis
NAMalaria, a disease caused by the parasite Plasmodium, is one of the world's...
Location
Radboud university medical center
Trial to Evaluate L9LS in Healthy Adults
PHASE1Background:
Malaria is a parasitic disease carried by mosquitoes in tropic...
Location
National Institutes of Health Clinical Center
Safety and Protective Efficacy of Genetically Attenuated PfSPZ-GA1 Vaccine in Healthy Dutch Volunteers
PHASE1This is a first-in-human, randomized clinical trial of PfSPZ-GA1 Vaccine (g...
Location
Leiden University Medical Center, Albinusdreef 2
An Efficacy Study of IV Boosting With ChAd63/MVA ME-TRAP
PHASE1Plasmodium falciparum Malaria remains a major global health problem with ap...
Location
NIHR Clinical Research Facility, Hammersmith Hospital
Controlled Human Malaria Infection (CHMI) After Immunization With Cryopreserved Plasmodium Falciparum Sporozoites Under Chloroquine Prophylaxis
PHASE1The purpose of the study is to determine the safety and tolerability of ID ...
Location
Radboud University Nijmegen Medical Centre
VAC 072-An Efficacy Study of R21/MM in Different Dose Schedules
PHASE1An open label, partially blinded clinical trial in which healthy volunteers...
Location
Guy's and St Thomas' NHS Foundation Trust
A Safety and Efficacy Study of ChAd63/MVA METRAP + RTS,S
PHASE1This is a clinical trial in which healthy volunteers will be administered e...
Location
Wellcome Trust CRF, Southampton General Hospital, University of Southampton